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Mona Sethi Gupta, Ph.D.

Freelance Science Writer

Dr. Gupta is a freelance science writer focusing on environmental and public health issues. She enjoys writing articles as well as non-fiction books on science, nature and environment. Mona obtained her Ph.D. degree in Toxicology from Texas A&M University and M.S. degree in Environmental Health from East Tennessee State University. After completing her post-doctoral fellowship at the Medical College of Virginia, Mona worked in industry as a staff toxicologist. She has taught courses at undergraduate and graduate levels in various areas of Biomedical Sciences and has 29 peer-reviewed publications and abstracts.

Dr. Gupta can be contacted at monasgupta@yahoo.com

Articles by Dr. Gupta

• Neurodevelopmental Disorders in Children: Autism and ADHD - April 14, 2008
  While the generally accepted causes of neurodevelopmental disorders like Autism and ADHD include genetic and environmental factors, a wide range of toxic chemicals in the environment have also been associated with these disorders.

Dr. Gupta's Resume

Education

• Ph.D. Toxicology

  Texas A&M University (TAMU), College Station, TX

  1999

• M.S.E.H. Environmental Health

  East Tennessee State University (ETSU), Johnson City, TN

  1995

• B.S. (Hons) Zoology

  University of Delhi, New Delhi, India

  1992

Experience

• 2003-2007: Affiliate Faculty

  Center for Environmental Sciences

  Virginia Commonwealth University

• 2005-2006: Toxicology Specialist

  Afton Chemical Corporation

  Health, Safety and Environment

  Richmond, VA

• 2002-2004: Senior Scientist Toxicology

  Toxicology Laboratory

  Arista Laboratories Inc.

  Richmond, VA

• 2000-2004: Reviewer

  Reviewer on editorial board of journal Environmental Toxicology and Pharmacology

Research Experience

• Postdoctoral Scientist

  Department of Pharmacology and Toxicology

  Medical College of Virginia, Richmond, VA

  2000-2002

• Research Assistant

  Genetic and Molecular Toxicology Laboratory

  Department of Veterinary Physiology and Pharmacology

  Texas A&M University

  1995 - 1999.

• Research Assistant

  Environmental Health Sciences Laboratory, ETSU

  1993-1994

Teaching Experience

• Environmental Toxicology (Graduate level course)

  Fall 2003

  Center for Environmental Studies

  Virginia Commonwealth University

• Introduction to Life Sciences

  Fall 2002

  Department of Biology

  Virginia Commonwealth University

• Biological Analysis in Environmental Health (Senior level course)

  Spring 1995

  Department of Environmental Health

  East Tennessee State University

• Introduction to Biostatistics (Junior level course)

  Fall 1994

  Department of Environmental Health

  East Tennessee State University

• Student Advisor

  1994-1995

  Department of Environmental Health

  East Tennessee State University

  Mentored undergraduate students on course and career options.

• Biology and Chemistry Tutor

  1993-1995

  Office of Student Tutoring Services

  East Tennessee State University

  Tutored undergraduate physiology, biochemistry, anatomy, physical-, organic- and inorganic-chemistry.

Selected Publications

• DeMasters GA, Gupta MS, Jones KR, Cabot M, Wang H, Gennings C, Park M, Bratland A, Ree AH, Gewirtz DA. 2004. Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089. J Steroid Biochem Mol Biol. 92(5):365-74.
• Farrell N, Povirk LF, Dange Y, DeMasters G, Gupta MS, Kohlhagen G, Khan QA, Pommier Y, Gewirtz DA. 2004. Cytotoxicity, DNA strand breakage and DNA-protein crosslinking by a novel transplatinum compound in human A2780 ovarian and MCF-7 breast carcinoma cells. Biochem Pharmacol. Sep 1;68(5):857-66.
• Polar M, Gennings C, Park M, Gupta M, Gewirtz D. 2003. Effect of the Vitamin D3 analog ILX 23-7553 on apoptosis and sensitivity to fractionated radiation in breast tumor cells and normal human fibroblasts. Cancer Chemotherapy and Pharmacology. 51(5), 415-21.
• Kim ND, Kaplan B, Gupta M, Amichay A, Lansky E, Livney T, Neeman I, Poirier D, Luu-The V, Nicholls P, Kirby A, Jiang W, Mansel R, Mehta R, Gewirtz D. 2002. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Research and Treatment. 71, 203-217.
• Gewirtz D, Gupta M and Sundaram S. 2002. Vitamin D3 and vitamin D3 analogues as an adjunct to cancer chemotherapy and radiotherapy. Review. Current Medicinal Chemistry-Anticancer Agents. 2, 683-690.
• Posner G.H., Crawford K.R., Peleg S, Welsh Jo-Ellen, Romu S, Gewirtz D, Gupta M.S. , Dolan P and Kensler T.W. 2001. A non-calcemic sulfone version of the vitamin D3 analog seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin. Bioorganic and Medicinal Chemistry, 9, 2365.
• Safe S, McDougal A, Gupta M.S. , and Ramamoorthy, K. 2001. Selective Ah Receptor Modulators (SahRMs): Progress towards development of a new class of inhibitors of breast cancer growth. Review. Journal of Women’s Cancer, v 3, 1.
• McDougal A, Gupta MS, Morrow D, Ramamoorthy K, Lee JE, Safe SH. 2001. Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats. Breast Cancer Research and Treatment. 66(2):147.
• Sundaram S, Chaudhry M, Reardon D, Gupta M and Gewirtz DA. 2000. EB 1089 enhances the antiproliferative and apoptotic effects of adriamycin in MCF-7 breast tumor cells. Breast Cancer Research and Treatment, 63, 1, 1-10.
• Barhoumi R, Mouneimne Y, Ramos K, Safe S, Phillips T, Centonze V, Ainley C, Gupta M and Burghardt R. 2000. Analysis of Benzo[a]pyrene partitioning and cytotoxicity in a rat liver cell line. Toxicological Sciences. 53, 2, 264.
• McDougal A, Gupta M.S. , Ramamoorthy K, Sun G and Safe S. 2000. Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane. Cancer Letters. 151, 2, 169.
• Gupta M.S, Miggins J, Parrish A, Ramos K, Womack J, Rodriguez L.V, Goldstein L.S, Holtzapple C, Stanker L and Safe S. 1998. Ah-receptor independent induction of CYP1A2 gene expression in genetically inbred mice. Environmental Toxicology and Pharmacology. 5, 205-213.
• Gupta M.S, McDougal A and Safe S. 1998. Estrogenic and anti-estrogenic activity of 16-hydroxy- and 2-hydroxy- metabolites of 17-estradiol in human breast cancer cells. Steroid Biochemistry and Molecular Biology. 67, 413-419.
• Ramamoorthy K, Gupta M.S. , Sun, G, McDougal A and Safe S. 1998. 3,3',4,4'-Tetrachlorobiphenyl exhibits antiestrogenic and antitumorigenic activity in the rodent uterus, mammary and human breast cancer cells. Carcinogenesis. 20, 115-123
• Gupta, M.S, Ramamoorthy K and Safe S. 1998. Antiestrogenic activity of 3,3',4,4'-tetrachlorobiphenyl and 3,3',4,4',5-pentachlorobiphenyl in T47D breast cancer cells. Organohalogen Compounds. 37, pp. 297.
• Ramamoorthy K, Gupta M.S. and Safe S. 1998. Aryl-hydrocarbon receptor mediated antiestrogenicity of diindolylmethane (DIM) and analogs in vivo and in vitro. Organohalogen Compounds. 37, pp. 321.

[last updated: 2008-04-14]